Theepithelialbarrierdysfunctionhas been recognized in a number of diseases, such as allergic asthma (Post et al., 2013),allergic rhinitis (Liu et al., 2012), food allergy (Liu et al., 2013).Inkidney, a filtration barrier consists of endothelialcells, basement membrane, and epithelial cells called podocytes.Failure to maintain the filtration barrier leads to a number of kidney disorders, such as massive proteinuria and nephrosis(Peti-Peterdi and Sipos, 2010). The pathogenesis of barrier dysfunction is not fully understood.

閱讀全文請見：Interleukin-13 promotes expression of Alix to compromiserenaltubular epithelial barrier function