Oxidativestressaltersglobalhistonemodification and DNAmethylation

作者:Yingmei Niu , ThomasL.DesMarais , ZhaohuiTong , YixinYao , MaxCosta 來源:醫學論壇網 日期:17-12-12

Reactiveoxygenspecies(ROS)suchassuperoxideanionradical,Hydrogenperoxide(H2O2),andhydroxylradicalaregeneratedendogenouslythroughmitochondriarespirationaswellasthrough exogenousoxidizingagentsincludingionizingradiation,heavy metals,andhypoxia.ROSaffectsawiderangeofbiologicalprocesses throughavarietyofmechanisms.Differenthypotheseshavebeen

閱讀全文請見:OxidativestressaltersglobalHistonemodification and DNAmethylation

關鍵字:Oxidativestress,Histone,demethylase,Hydrogenperoxide

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