近期，昆明醫科大學藥學院暨雲南省天然藥物藥理重點實驗室等研究人員發表《基於假病毒篩選抗病毒藥物的研究進展》研究，該文章發表於2015年3期的《國際藥學研究雜誌》上。

假病毒是一種整合其他病毒囊膜糖蛋白所形成的具有外源性病毒囊膜、而自身基因組仍保持著源病毒基因組特性的一類病毒。假病毒因喪失了病毒的自我複製能力，具有安全性高等優點，已被廣泛用於包括HIV、H5N1、HCV等病毒的研究。本文介紹了基於假病毒技術進行研究的優勢及局限性，還通過總結大量研究成果闡明了利用假病毒技術進行藥物篩選的可行性與有效性。假病毒藥物篩選平台作為一種新型、安全、可靠的實驗手段，將為抗病毒藥物的研究做出更多的貢獻。

Abstract：

The pseudotype virus is a virus nucleic acids packaged by another virus envelope protein, to form the virus with the exogenous virus envelope and maintain virus genome characteristics of itself. Due to the loss of its ability to self-replicate and high safety, pseudoviruses are widely used as safe substitutes for infectious virus in virology studies, such as HIV, H5N1 and HCV Here we will introduce the advantages and limitations of pseudoviruses, and through summarizing a large number of research achievements, we prove pseudoviruses are feasible and effective as an antiviral drug screening platform. The platform is safe and reliable and it will make more contribution in antiviral drug research.